الفهرس 
Introduction and the aim of the workOnly 14 pages are availabe for public view
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Abstract
Antiphospholipid syndrome IS a multi-system disorder characterized by persistently elevated antiphospholipid antibodies, arterial and/or venous thrombosis, thrombocytopenia or recurrent abortions (George, 1997). I , ’ Cardiolipin is a member of the family of phosph’lipiqs and is considered now the most useful antigen used for the " ~ "ntiphospholipid assay. Furthermore, it shows the strongest association with symptomatic disease (Asherson et al., 1989) and the presence of these antibodies may , . be an indicator of a prethrombotic state in patients with no eV,idence of mitoimmuile disease (McCrea et al, 1991). I The risk of thrombosis, thrombocytopenia (Harris et al., 1986) and recurrent fetal loss (Loizou et al., 1988) has been associated with high levels of ACAs and ’gG-isotype is more strongly associated with the clinical complications compared with IgM-isotype (Harris et al., 1986). APAS followed by venous thrombosis. Isolated thrombocytopenia which is a decrease in platelet count less than 150 x 10’ /mm’ in peripheral blood cell count with normal or increased other cell lines count, has been estimated recently in HCY patients as an usher of APS in these cases waiting for the ACAs positivity, the more specitlc marker (EL-Sherif et al., 200 I). The above considerations have triggered us to study the issue of isolated thrombocytopenia and APS in patients with chronic liver disease.