الفهرس 
Introduction And Aim Of WorkOnly 14 pages are availabe for public view
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Abstract
• NO and CO play some important roles in the pathophysiology of neonatal sepsis. • Plasma NO and CO levels are elevated in newborn infants with sepsis. • This elevation is independent of gestational age, gram stain of the isolated pathogen, and whether it is early or late onset sepsis. • There are no significant differences in plasma levels of NO and CO between septic preterm and septic full term infants. • Assay of plasma CO and NO may have some clinical values to estimate the severity of sepsis and progression to septic shock. • Plasma NO and CO are higher in patients requiring inotropic and vasopressor support. • Plasma CO is higher in non-survivors. Plasma NO is not statistically different between survivors and non-survivors. • Elevation of plasma NO> 41.7 umol/I, and plasma CO > 30.1 umol/I is significantly associated with sepsis. • Plasma CO is more sensitive for diagnosis of sepsis than plasma NO. • The elevation in CO production is related to tile increased NO production . • Plasma NO and CO are positively correlated with serum eRP.