الفهرس 
introduction and aim of the workOnly 14 pages are availabe for public view
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Abstract
This study was carried on 70 patients with variety of malignant neoplasms involving the head and neck. ” The results obtained can be summarized as following:- ” In the prospective group - TSH exhibited two phases significant initial decrease at 2 weeks after radiotherapy followed by gradual increase - T3 and T4 showed slight temporary increase after 2 weeks of radiotherapy followed by gradual significant decrease. - Anti TPO-Ab increased from the 3rd month forwards. - FTI showed significant decrease after the 6th month. ” In the retrospective group - TSH level showed statistically significant elevation than the base line between 3,5 year. - Anti TPO-Ab increased significantly in the 4th year ” Chemical hypothyroidism was noticed at higher rate than clinical hypothyroidism in the 1st 3 years after radiotherapy in both groups. ” Chemical hypothyroidism was the earliest dysfunction noticed in the retrospective group( observed after 6 month). ” Clinical hypothyroidism was observed later during follow up ” The use of adjuvant chemotherapy did not influence the incidence of thyroid dysfunction after irradiation. ” Increase of the dose was associated with increase the incidence of nodularity and inhomogenity in both groups. ” Abnormal sonography and scan was more frequent between cases with hypothyroidism or hyperthyroidism than euthyroid patients. Thyroid gland- thyroiditis - Thyrotoxicocis - radiation injury - hypothyroidism - benign and malignant thyroid neoplasms.