الفهرس 
Introduction&Aim of the workOnly 14 pages are availabe for public view
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Abstract
The aim of the present work was to study homocysteine plasma level in our patients with type 2 diabetes mellitus and try to find relationship between its plasma levels and some concomitant diabetic complications. The study comprised sixty type 2 diabetic patients with different micro and macrovascular complications, The diabetic patients were 30 male and 30 females with age ranging from 40 to 62 years (51.77 5.5.47) years they were selected from medical inpatient and outpatient in Mansoura University hospital, the diagnosis of type 2 diabetes mellitus was based on age at onset, clinical course of the disease and therapeutic history. All cases are subjected to the following assessment, Thorough medical history, Clinical examination including , general, chest, cardiac, abdominal and neurological examination stressing on blood pressure Anthropometric measurements Including, Height, weight and body mass index, Waist circumference and hip circumference and WHR Waist hip ratio) was calculated as waist/hip. Electrocardiogram (ECG) was done to all patients and control subjects , Fundus examination of the eye and Doppler examination to detect peripheral vascular ischemia of the lower limbs. From this study, it is concluded that hyperhomocysteinemia is present in type 2 diabetes especially in patients with concomitant macrovascular complications. Therefore hyperhomocysteinemia is now considered as a definite risk factor for vascular complications therefore routine screening of type 2 diabetic patients for hyperhomocysteinemia is recommended and patients with elevated homocysteine levels should be treated thoroughly.