الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
Background. In 1989, the hepatitis C virus (HCV) was cloned and identified as the major cause of parentrally transmitted non-A, non-B hepatitis (NANBH). Renal patients have a potential risk of developing post-transplantation hepatitis C due to: - Multiple blood transfusions.- Non-transfused hemodialysis patients.- Donor organs. This work aimed at: 1-identify the relation between HCV& transplant glomerulopathy. 2-identify the role of cryoglobulins in HCV-induced GN. 3- study the impact of HCV on graft &patient survival. Methods. The material of this work included 273 live-donor kidney transplant recipients who where transplanted between 1993-1996. They were investigated for: anti-HCV antibodies, HCV RNA PCR, 24 hour urinary protein, chronic hepatitis, C3&C4, rheumatoid factor and cryoglobulins. Anti-HCV negative patients served as a control group. Results&Conclusion.1-42% of ELISA-positive patients developed at least a transient elevation of ALT level after transplantation. 2-Our anti-HCV positive recipients had a lower number of acute rejection episodes than anti-HCV negative ones. 3- A statistically significant difference in the number of acute rejection episodes was found being higher in recipients with nephrotic-range proteinuria and independent on the serology whether positive or negative.4- of our patients in both groups was positive for cryoglobulins.5- Nephrotic-range proteinuria, independent on serology, was associated with poorer graft outcome . Key words: (not more than Ten ): Kidney Transplantation - Hepatitis C Virus.