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العنوان
The effects of some commonly used drug absorption enhancers on the normal histological structure of oral mucosa /
المؤلف
El-Hawary, Yousry Mahmoud Aly.
هيئة الاعداد
باحث / يسري محمود علي الهواري
مشرف / ابتسام محمد فتحي
مشرف / عصام فاروق سوسة
مشرف / فاروق محمد صقر
مشرف / محمد احمد عاشور
الموضوع
Oral Biology. Oral mucosa - Diseases.
تاريخ النشر
2001.
عدد الصفحات
162 p. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
طب الأسنان
تاريخ الإجازة
1/1/2001
مكان الإجازة
جامعة المنصورة - كلية طب الأسنان - قسم بايولجيا الفم
الفهرس
Only 14 pages are availabe for public view

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from 170

Abstract

Sodium lauryl sulphate, bile salt, bile acid and, sodium salicylate are used in treatment of several medical problems.
In our study we studied the local effects of these drugs which were commonly used as absorption enhancers on the histological structure of the buccal mucosa of white rabbits.
One hundred and thirty (130) rabbits were used in this study.
In the control group we put the patch on the buccal mucosa against molars of the rabbits without drugs, in group B we used sodium lauryl sulphate in concentrations 1 %, 2 %, 3 %, with the patch on the buccal mucosa of the rabbits at the same site of control group, group C using bile salt with concentrations 1 %, 2 %, 3 %, as group.
This research was conducted to study the effect of some Pharmaceuticals stimuli such as absorption ( sodium Uraijl sulfate , bile salt , sodium salicylate ) on the mucous membrane lining the advisory of services inside the mouth of this research was conducted on 130 rabbit .
Rabbits were divided into Sthmjmoat each group of twenty - four rabbit Maada control group containing ten rabbits only.
Used in this research , several studies ( histological study , study the study of microscopic -mail ).
* In the histological study :
The samples are to become sectors Brafinah and these pigmentation four sectors Sabgat .
* In study Alhustokimaaúah :
Frozen samples and longer to detect on Aanzimi activity of acid and alkaline phosphatase .
* In the study microscope mail :
Cut tissue samples into small Bblukat and submerged in a solution and then use the acid solution Alalik secondary installer for two hours. * Results :
- Results histological
. Disturbances in the upper layers of human tissue in the mucous membrane lining the advisory . Services
. Swelling occurs within a few human cells in the upper fourth group of rabbits.
. Significant swelling in the upper human cells .
2 - Results Alhustokimaaúah :
The results Alhustokimaaúah when compared to the control group the following:
Average interaction in the control group and the sixth in all layers of human tissue , while in the second group and the third , fourth and fifth no reaction medium in the basal and middle classes of the human fabric .
3 - Results using the electron microscope :
The second and third group showed minimal changes inside and outside of human cells compared to the control group , while the fourth and fifth groups found changes of the cell organelles and note when compared to the control group , as there is also a small increase in the distances Albin Phones in the second and third.