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العنوان
Role of interleukin-­8 in prediction of acute rejection after allograft renal transplantation /
المؤلف
Nassar, Mogahid Yahya Hassan.
هيئة الاعداد
باحث / مجاهد يحيى حسن نصار
مشرف / فرحة عبدالعزيز الشناوي
مشرف / اماني مصطفى اسماعيل
مشرف / منال عبدالغفار فوده
الموضوع
Interleukin-8. Graft rejection. Acute renal failure. Kidneys - Transplantation.
تاريخ النشر
2002.
عدد الصفحات
108 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الطب
تاريخ الإجازة
01/01/2002
مكان الإجازة
جامعة المنصورة - كلية الطب - Department of Clinical
الفهرس
Only 14 pages are availabe for public view

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Abstract

After renal transplantation the expression of IL-8 was increased in tubular cells, suggesting an important role for this protein in the ongoing allograft rejection. We studied the value of IL-8 determinations as an early marker in renal transplant rejection diagnosis. Serum samples were analyzed with an IL-8spesific sandwich enzyme-linked immunosorbent assay. IL-8 serum concentration increase during acute renal rejection episodes, suggesting a role of IL-8 in the process of rejection and its estimation may be of value in non-specific diagnosis of rejection but have no role in the prediction of acute renal rejection. Detection of IL-8 mRNA expression has no role in the diagnosis neither the prediction of acute renal allograft rejection.