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Abstract Humans and animals are commonly exposed to EMFs. The effects of chronic exposure to environmental electric and magnetic fields have been the subject of intense research leading to no definite answers. This work is mainly concerning with the biological effects of EMF specially the SMF and the ELFEMF, and their effects on antioxidants as well as immunological and physiological responses. Two exposure systems were designed; the first is mainly a perforated Perspex box having several magnet discs on its four walls and the floor, which is the SMF system. The second is made of two Helmholtz coils made of copper wires, with a calculated electric current passing through them, the Perspex cage is located in the centre between the Helmholtz coils, the ELFEMF generated in the cage is measured and calculated in each case. The used animals were male mice weighting 1820 gm, divided to three groups as control, SMF and ELFEMF exposed groups. The exposure of mice was for a month, after that they were all scarified at the same time where blood, spleen and liver were collected for biochemical, haematological, and immunological studies were carried out. |