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العنوان
Behaviour of cyclohexenone derivatives towards photooxygenation reactions /
المؤلف
Ibrahim, Mona El­-ayed Mohamed.
هيئة الاعداد
باحث / مني السيد محمد إبراهيم
مشرف / محمد محمود أبوالذهب
مشرف / وفاء سلامه حمامه
مشرف / حنفي حسن زعرب
الموضوع
Cyclohexenone. Photooxygenation. Epoxidation. Photobinding.
تاريخ النشر
2003.
عدد الصفحات
84 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
Organic Chemistry
تاريخ الإجازة
01/01/2003
مكان الإجازة
جامعة المنصورة - كلية العلوم - Department of chemistry
الفهرس
Only 14 pages are availabe for public view

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Abstract

The purpose of this study is to prepare hyDROPeroxide derivative which are expected to have a biological effect on DNA. First, photooxygenation of 2­cyclohexenone­6­carboxylate derivative: 3,5­diphenyl­3­(4`­methoxyphenyl)­5­phenyl­3(4`­chlorophenyl)­5­phenyl to give hyDROPeroxide derivatives in addition to hydroxyl derivatives. Second, photooxygenation of 3­methyl, 5­phenyl­2­cyclohexenone­6­carboxylate to give the expected hyDROPeroxide. Third, photooxygenation of 3­styryl, 5­phenyl­2­cyclohexenone­6­carboxylate to give the hydroxyl derivative instead of the endoperoxide derivative.Fourth, photoxygenation of 5­styryl, 3­phenyl­2­cyclohexenone­6­carboxylate to give hyDROPeroxide in addition to hydroxyl derivative. Fifth, application of the hyDROPeroxide derivative obtained on ATP degradation to give phosphoric acid. Sixth, cleavage of DNA by hyDROPeroxide derivative prepared. Spectral measurements as IR, 1H­NMR, Mass, 13C­NMR and elemental analysis were used to determine the structures of the resulting reaction products.