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Abstract The purpose of this study is to prepare hyDROPeroxide derivative which are expected to have a biological effect on DNA. First, photooxygenation of 2cyclohexenone6carboxylate derivative: 3,5diphenyl3(4`methoxyphenyl)5phenyl3(4`chlorophenyl)5phenyl to give hyDROPeroxide derivatives in addition to hydroxyl derivatives. Second, photooxygenation of 3methyl, 5phenyl2cyclohexenone6carboxylate to give the expected hyDROPeroxide. Third, photooxygenation of 3styryl, 5phenyl2cyclohexenone6carboxylate to give the hydroxyl derivative instead of the endoperoxide derivative.Fourth, photoxygenation of 5styryl, 3phenyl2cyclohexenone6carboxylate to give hyDROPeroxide in addition to hydroxyl derivative. Fifth, application of the hyDROPeroxide derivative obtained on ATP degradation to give phosphoric acid. Sixth, cleavage of DNA by hyDROPeroxide derivative prepared. Spectral measurements as IR, 1HNMR, Mass, 13CNMR and elemental analysis were used to determine the structures of the resulting reaction products. |