الفهرس 
INTRODUCTION AND AIM OF THE WORK
Leptin receptors (OB-R)Only 14 pages are availabe for public view
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Abstract
Introduction : Regional anesthesia either spinal or epidural is more commonly performed for various lower abdominal surgery. Subaracheniod block being more preferable due to its rapid and consistent effect . Traditionally , lidocaine solution was the commonest preparation for spinal anesthesia , but its neurological complications in the form of transient neurological manifestation limited its use . Hypobaric lidocaine had been used in spinal anesthesia but its duration of action was short and its motor and sensory bock was dense enough to overcome the painful surgical stimulation . Patient and methods : This study was carried out on 36 male patient submitted for elective inguinal hernia repair. The patients were allocated into 3 groups of 12 patient each according to the dose of intrathecal meperidine, group I received 15 mg meperidine , group II received 17.5 mg meperidine , group III received 20 mg meperidine plus 20 mg intrathecal hypobaric lidocaine for all groups. All patients were monitored regarding haemodynamics, sensory and motor block intraoperativly and 24 hours postoperatively. Results: This study reviled that 20mg intrathecal meperidine added to 20mg hypobaric lidocaine gave the longest duration of postoperative analgesia with least side effects which allows the early discharge of the patients from the postanethetic care unit and hospital .. Conclusion : from the study , we can concluded that meperidine at a dose of 20mg provides long duration of postoperative analgesia than meperidine at dose of 17.5mg and 15mg without increase in the peak sensory level , sensory and motor block duration . Also there was no recorded any side effects . All these advantages allow the early discharge of the patient from the post anesthetic care unit and hospital