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العنوان
Analgesic outcome of intrapleural infusion of ropivacaine versus bupivacaine following elective upper abdominal surgery /
المؤلف
Abd El-­Maksoud, Ayman Abd El­-Hady.
هيئة الاعداد
مشرف / أيمن عبدالهادي عبدالمقصود
مشرف / أشرف محمد وهبة وفا
مشرف / ولاء صفاء الدين الخربوطلي
مشرف / أمل رشاد رياض
مشرف / مصطفي محمد علي السعيد
الموضوع
Intrapleural analgesia. Pain score. Postoperative pain. Amino acids - Physiological effect.
تاريخ النشر
2005.
عدد الصفحات
100 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
العناية المركزة والطب العناية المركزة
تاريخ الإجازة
1/1/2005
مكان الإجازة
جامعة المنصورة - كلية الطب - قسم التخدير والعناية المركزة الجراحية
الفهرس
Only 14 pages are availabe for public view

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from 115

Abstract

Control of acute pain in postoperative period represents a rapidly expanding area of research in our specialty. Many strategies have been adopted to achieve this goal and regional techniques have acquired more importance by time. Intrapleural analgesia represents one of these techniques. This study was designed to compare the effectiveness of intrapleural ropivacaine versus bupivacaine in postoperative pain relief following elective upper abdominal surgery. Forty patients were included in this study (ASA I&II) of either sexes with age ranging from 20 to 60 years. The candidate patients were scheduled for different elective abdominal surgeries with upper abdominal incision. The studied patients were divided into two groups: Group A (Bupivacaine group): An initial dose of 20 ml of 0.5% bupivacaine and fentanyl l<U+00B5>g/kg was injected as a bolus dose followed by continuous infusion of 0.25% bupivacaine at a rate of 0.1 mg/kg/h for 8 hours then at a rate of 0.05 mg/kg/h for the next 8 hours. Group B (Ropivacaine group): An initial dose of 20 ml of 0.5% ropivacaine and fentanyl l<U+00B5>g/kg was injected as a bolus dose followed by continuous infusion of 0.25% ropivacaine at a rate of 0.25 mg/kg for 8 hours then at a rate of 0.125 mg/kg/h for the next 8hours. In both groups, fentanyl 0.2<U+00B5>g/kg/h was added to the local anesthetic infusion. The quality of analgesia in bupivacaine group was better than that of ropivacaine group at any time of the observation period. Prince Henry pain scores of bupivacaine group were significantly lower than ropivacaine group at 2, 4, 6, 8 hours postoperatively. Haemodynamic variables were stable in both groups apart from the significant decrease of heart rate and mean arterial blood pressure in bupivacaine group 15 minutes after induction. Vomiting occur more frequently in patients of bupivacaine group (20%) than those of ropivacaine group (5%), there were no recorded other complications such as pneumothorax, hypotension or respiratory depression.