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العنوان
Immunohistochemical study of bcl-­2 expression in mucoepidermoid carcinoma of salivary glands /
المؤلف
Farag, Doaa Abd Allah.
هيئة الاعداد
باحث / دعاء عبدالله فرج
مشرف / عزة عباس السيسي
مشرف / مها محمد ابوهاشم
مشرف / هالة عصام فكري.
الموضوع
Cancer. Salivary glands. Mucoepidermoid carcinoma. Salivary glands.
تاريخ النشر
2003.
عدد الصفحات
136 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
طب الأسنان
تاريخ الإجازة
1/1/2005
مكان الإجازة
جامعة المنصورة - كلية طب الأسنان - Oral Pathology Department
الفهرس
Only 14 pages are availabe for public view

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Abstract

from the results of present of the present work, it could be concluded that: ­ There might be an inverse correlation between BCL­2 staining index versus both MEC grades and MEC score according to the AFIP. ­ Low grade MEC might have high expression of BCL­2. ­ Intermediate grade MEC might have variable expression of BCL­2. ­ High grade MEC might have less expression of BCL­2. ­ The high BCL­2 expression in association with minimal anaplasia and interacystic space >20% might indicate a tumor of MEC at an earlier stage of its progression. ­ The least BCL­2 expression together with severe anaplsia and minimal intracytic space (<20%) might indicate that the MEC tumor is in its late stage of malignancy. ­ The positive expression of Bcl­2 detected in epidermoid, intermediate, and columnar cells could be due to the contribution of these cells in the slow progression of the tumor grade.