Search In this Thesis
   Search In this Thesis  
العنوان
Synthesis of certain benzimidazole and fused benzimidazole derivatives of pharmaceutical interest \
المؤلف
Abd El­-Maguid, Abd El-­Basset Ahmed.
هيئة الاعداد
باحث / عبدالباسط أحمد عبدالمجيد
مشرف / حسن محمد حسن عيسى
مشرف / علاء الدين محمود برغش
مشرف / سحر محمد إبراهيم بدر
مناقش / شمس الدين أبوالعزم شمس الدين
مناقش / فاطنة النبوية السيد جودة
الموضوع
Benzimidazole. Pharmaceutical Organic Chemistry.
تاريخ النشر
2006.
عدد الصفحات
135 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الصيدلة ، علم السموم والصيدلانيات
تاريخ الإجازة
1/1/2006
مكان الإجازة
جامعة المنصورة - كلية الصيدلة - Department of Pharmaceutical Organic Chemistry
الفهرس
Only 14 pages are availabe for public view

from 157

from 157

Abstract

In the present investigation, new series of benzimidazole compounds that contain oxadiazole, phenyltriazole, thiazolidines and pyrmidines, were prepared. Also, fused benzimidazole rings were prepared such as triazinobenzimidazoles, pyrimidopyrolobenzimidazoles. The structures of these compounds were determined by elemental microanalysis, 1H­NMR, IR and mass spectroscopy. All the newly synthesized final compounds were subjected to in vitro antimicrobial screening. The results showed that most of the compounds under test exhibited different degrees of antimicrobial activity. Nine compounds were subjected to antiviral and cytotoxicity assays.