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Abstract Fibrinogen, fibrinolytic system and AT III level Iwere studied in the venous blood of 34 newborns during the first 3 days of life. These infants included 13 full term, 8 healthy preterms 5 asphyxiated preterms ’(4 diagnosed as I.R.D.S. and one as central depression) and 8 I.D.Ms. newborns. They were subjected to the following tests : 1. Thrombin time in seconds. 2. Fibrinogen content in mg/litre.3. F.D.Ps. in g/litre. 4. Euglobulin clot lysis time. 5. At III level ing/litre. No significant difference in fibrinogen content in healthy and asphyxiated preterms compared to normal full term newborns or between healthy and asphyxiated preterms was found. No significant correlation between fibrinogen con¬tent and gestational age was found suggesting that fibrinogen is not gestational age dependent. No furthur correlation between fibrinogen and birth weight or post-natal age were found. A significant increase in fibrinogen content (p < 0.05) in I.D.Ms. than in full term newborns. |