الفهرس 
Aim of the work
Materials and methodsOnly 14 pages are availabe for public view
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Abstract
Quality Control is defined by ISO as ”the operational techniques and activities that are used to satisfy quality requirements.” An important part of the quality control is the Quality Assessment: the system of activities to verify if the quality control activities are effective or not. - Quality control is primarily aimed at the prevention of errors. However, it remains inevitable that errors are made. Therefore, the control system should have checks to detect them. Aim of the work: - This study aims to 1- Evaluate the effect of some pre-analytical and analytical factors influencing laboratory test results. 2- Asses the analytical performance among different clinical chemistry laboratories in main hospital and specialized medical centers of Mansoura University. 3-Establish the concept of Quality management among these laboratories. Methods: - The study is designed to evaluate the role and magnitude of deviation of laboratory results due to various pre-analytical conditions. In addition, analytical performance was evaluated in clinical chemistry laboratories in most of Mansoura University Specialized medical centers. This was achieved by application of various quality control parameters (Levy-Jennings chart and Westgard rules). Results: Results are presented in two main directions: A- Pre-analytical variables including hemolysis where Albumin showed no significant change in hemolyzed samples compared to non hemolyzed ones. Total bilirubin, ALT and AST showed significant increase after hemolysis. Food intake showed non significant difference in albumin, total bilirubin, ALT, AST, cholesterol, creatinine and uric acid and a highly significant increase in glucose and triglycerides. B-Assessment of performance of clinical chemistry laboratories in some Mansoura University Hospitals Conclusion: - Avoid pre-analytical influences by: a- Rejection of hemolyzed samples. b- Proper adjustment of the duration of fasting for fasting samples, as well as strict adherence to protocols of fasting and dieting, both before and on day of sampling. Drug intake should be taken into consideration. c- Avoiding the use of excess liquid anticoagulant to avoid dilution of sample. d- Avoiding the use of a tourniquet and if necessary it should be applied for a minimal duration with gradual release. Quality control, pre-analytical, Levy-Jennings charts, Westgard rules.