الفهرس | Only 14 pages are availabe for public view |
Abstract Study the bad effect of epilepsy o pregnant rats treated with lamotrigine and valproate to study there effect on pregnant rats and their newborn we found that all the treated group showing some bad effects. Effect on pregnant rats:1-Decrease body weight if compared with the control.2-Degeneration of the liver cells and showing pyknotic neuclei.3-Degeneration of the renal tubule of the kidney.4-Degeneration of myocardial fibers.5-Degeneration of cartilage cell in the epiphysis of femer bone.Effect on newborn:1-Decrease body weight, size and crown rump length.2-Histopathological effect on eye, liver, kidney and heart. |