الفهرس 
The wheezy infantOnly 14 pages are availabe for public view
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Abstract
Wheezy infants is that infant having recurrent or persistent wheezing for more than four weeks. Wheezing is a relatively frequent and particularly troublesome manifestation of a obstructive lower respiratory tract disease in infant. The infant with persistent or recurrent wheezing during the first two years of life poses a diagnostic dilemma, which can be a source of anxiety to both physicians and parents. Recurrent wheezing in infancy may be associated with many environmental and genetic factors, family history of atopy, high household humidity levels, parental smoking and wooden floors are risk factors for wheezing in infants. In the current study, we evaluated tidal breathing and compliance, resistance with CD-4 IL-5 gene expression among wheezy infants and neurologically impaired infants and children. 71 patients were enrolled in the study and divided into 3 groups: group I: wheezy infants, group II and III are control groups. Group I involved 41 patients (25 (61.0%) males and 16 (39%) females) with mean age of 12.1 ± 5.69 months. Analyzing demographic, clinical and laboratory parameters in the studied groups has revealed interesting results. It has been shown that wheezy infants are characterized by positive family history of BA than the control group. Tidal breathing analysis in the studied groups has demonstrated that wheezy infants are generally characterized by obstructive pattern of pulmonary functions in the form of prolonged expiratory time, decreased tI / tE Ratio and tPTEF/tE, increased RrsSO and decreased CrsSO Further analysis of laboratory markers in wheezy infants showed that IL-5 positive cases has marked obstructive pattern parameters than IL-5 negative cases. This also applied to Ig E positive cases and oesinophilic%. In addition, it was noted than many factors are more associated with obstructive pattern in tidal breathing analysis in wheezy infants. These include non-breast feeding, atopy, positive history of BA, +ve barium study for GERD, IL-5 +ve cases, IgE + ve cases. Conclusively, it has been shown that wheezy infants are characterized by marked obstructive pattern. Clinical and laboratory paramteres traditional associated with asthma pathogenesis contribute to the development of this pattern in wheezy infants.