الفهرس 
Introduction and Aim of the WorkOnly 14 pages are availabe for public view
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Abstract
The present study aimed to have additional information about SCA in Egypt especially in a costal area such as Damietta. This is because there is no sufficient works on this serious disease on this area before. In the present study, 700 samples of both sexes were involved. These samples were divided into three groups according to their ages. Haemoglobin concentration was measured in all groups which indicated that there were 15 cases of anemic children among the third group, while the other groups (group I, group II and group III) have normal haemoglobin concentration. According to the previous results, percents of the haemoglobin types were determined from haemoglobin electrophoresis of all groups by using PAGE techniques. The resulted gels were then analyzed using Gel Pro Analyzer Program. The results obtained from this technique showed that, there were 15 anemic cases from group III with sickle cell disease while, group I (neonate) have a higher value of HbF and group II and group III have a higher values of HbA. Also, the concentrations of zinc and iron in both erythrocytes and plasma were determined from ten cases of SCA and 31 samples of the normal groups (group I, group II and group III). In SCA samples zinc and iron in erythrocytes was significantly decreased than that found in the other normal groups (group I, group II and group III). But, plasma iron was found to be significantly increased when compared with the normal samples of group I, group II and group III, while plasma zinc value was significantly lower than that in the other groups. In conclusion, SCA was found to be 2% of 700 cases studied in Damietta area.