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العنوان
Charcterization and determination of certain pharmaceutical piperazines /
المؤلف
Habeeb, Fawzia Ahmed Ibrahim.
هيئة الاعداد
باحث / فوزية أحمد إبراهيم حبيب
مشرف / م. س. رزق
مشرف / م. إ. والاش
مشرف / أ. أ. أبو عوف
الموضوع
Piperazines. Analytical chemistry.
تاريخ النشر
1980.
عدد الصفحات
93 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الصيدلة ، علم السموم والصيدلانيات (المتنوعة)
تاريخ الإجازة
01/01/1980
مكان الإجازة
جامعة المنصورة - كلية الصيدلة - Department of analytical chemistry
الفهرس
Only 14 pages are availabe for public view

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from 123

Abstract

The widespread use of piperazine and its salts, in the treatment of worm infections, makes it desirable to search for a convenient method, for its microanalysis in its pharmaceutical dosage forms. Spec­ trophotometry has been chosen for this purpose. Acc­ ordingly, the aim of this work, is to study the spec­ trophotometric behaviour of piperazine derivatives and complexes with many reagents, so that one would be
able to adopt the best conditions for a precise and accurate determination for pure drug or its dosage forms.This thesis consists of four parts.
Part I.
This part includes general introduction on the chemistry, methods of preparation and clinical uses
of piperazine and its se.lta, also it includes a detailed presentation of the different methods of analysis for the salts under investigation.
PART II, III, IV;
These parts of the thes provide the experimental works done by the authoress
Part II.
As piperazine (heterocyclic nuclei ), in gene­ ral neither exhibit absorption in u.v. region nor in visible range of spectrum, this part deals with the
formation of N-nitroso piperazine which has an absorbance in the u.v. region by the reaction of piperazine and its salts with nitrous acid at pH 2.3-2.6 using.