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العنوان
Different methods for uterine artery occlusion versus myomectomy for management of symptomatic uterine fibroid /
المؤلف
Zaid, Abd El-Hady Abd El-Hady Mohammad.
هيئة الاعداد
باحث / عبدالهادى عبدالهادى زايد
مشرف / عبدالمجيد فتحى مشالى
مشرف / أحمد إبراهيم فــوده
مشرف / طلال أحمد عامر
مشرف / عبدالجواد المتولى عبدالجواد
الموضوع
Uterine fibroids-- Treatment. Myomectomy‎.
تاريخ النشر
2008.
عدد الصفحات
170 p. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
أمراض النساء والتوليد
تاريخ الإجازة
1/1/2008
مكان الإجازة
جامعة المنصورة - كلية الطب - التوليد وأمراض النساء
الفهرس
Only 14 pages are availabe for public view

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Abstract

Introduction: Fibroids are the most common benign tumor in women, affecting about 20 – ‎‎40% of women in reproductive age. Among the available modalities for treating ‎leiomyoma, hysterectomy is the most frequently performed method. ‎ Aim of work: To evaluate the safety and efficiency of laparoscopic bipolar coagulation of ‎uterine vessels in treating symptomatic fibroids.‎ Patients and methods: In current study; one hundred patients presented by abnormal ‎bleeding per vagina due to presence of uterine fibroid submitted to one of 3 procedures; 40 ‎patients submitted to LOUA, 20 patients to embolization of uterine arteries and last 40 ‎patients submitted to myomectomy. All of these patients addressed failed hormonal ‎therapy, counseled extensively regarding; potential risks, benefits, curative nature, fertility ‎issues regarding each procedure and informed written consent was obtained from all ‎patients. Post procedure follow up at 3, 6, 12 months for improvement of bleeding, ‎reduction in uterine and myoma volumes (ultrasound assessment), decrease in uterine ‎blood flow (Doppler ultrasound on both uterine arteries). ‎ Results: From 40 patients submitted to LOUA, 36 patients (90%) underwent technically ‎successful LOUA, 32 of them (88.9%) showed improvement of bleeding. Similar results ‎had been observed in perimenopausal & premenopausal cases (100% versus 86.7%) (P = ‎‎0.248) and also metrorrhagia and menorrhagia patients (90% versus 88.48%) (P = 0.094). ‎Reduction of uterine and myoma volumes for patients underwent LOUA had been ‎observed through ultrasound follow up with higher reduction in myoma size than uterine ‎size (78.8% versus 64.6%). Reduction of uterine and myoma volumes by US in LOUA ‎patients had been similar in; peri and premenopausal women (average reduction 63.9% & ‎‎75.04% versus 65.4% & 80.04%) (P = 0.199 & 0.320 respectively), patients with myoma ‎size  5 cm and those with myoma size > 5 cm (average reduction 64.9% & 78.5% versus ‎‎65.02% & 79.7%) (P = 0.779 & 0.703 respectively) and in intramural and submucous ‎myoma cases (average reduction 64.4% & 79.8% versus 65.80% & 76.09%) (P = 0.251 & ‎‎0.241 respectively) and better results had been noted in multiple than solitary myoma ‎cases (average reduction 71.7% & 84.8% versus 63.8% & 78.3%) (P = 0.420 & 0.030 ‎respectively).‎ Conclusions: It had been concluded that uterine artery occlusive methods (namely UAE ‎and LOUA) are a promising new methods for treatment of uterine myomas with a ‎comparable effects to that of myomectomy and fewer side effects than myomectomy. ‎LOUA is as effective as embolization as a treatment for fibroid related bleeding with fewer ‎complications than embolization.‎