الفهرس 
Aim of the WorkOnly 14 pages are availabe for public view
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Abstract
Brucellosis still remains one of most common bacterial zoonosis, with over half a million new cases annually and prevalence rates in some countries exceeding ten cases per 100 000 population. Despite being endemic in many developing countries, brucellosis remains underdiagnosed and under-reported. Furthermore, since brucellosis is an important cause of veterinary morbidity and mortality, the disease can also cause important economic losses in developing countries. Although brucellosis in human beings is rarely fatal, it can be severely debilitating and disabling. This study was conducted on a sample from 8 districts of Dakahliya governorate of them (25.4%) from Mansoura City, (16.9%) from Dekernis district, (11.9%) from Mineat Alnasr, (11%) from Aga, (11%) from Alsenbelaween, (9.3%) from Belqas, (7.6%) from Almanzalla and lastly (6.8%) from Talkha. The study started by interview and filling of questionnaire followed by Collection of blood samples of 3ml of venous blood from each participating subject to be examined for presence of Brucella antibodies in serum, The serum agglutination test is performed with a standardized antigen preparation. A positive test consists of a 4-fold rise in titer or a single titer of 1/80 or higher. The study results detect that the infection rate of brucella among the high-risk occupationally exposed group in Dakahliya governorate was (41.5%) which may be considered a fairly high prevalence rate. From the epidemiological point of view, the current study results reveal that (47%) of positive brucella cases were caused by brucella abortus alone while (53%) of positive brucella cases were caused by both brucella abortus and brucella melitensis which emphasized that Brucella Melitensis alone was not responsible for infection in any case. In addition, the age group of 31-40 years was the most commonly affected with brucellosis. Moreover, the prevalence of brucella infection among females was higher than among males. Also the prevalence of brucella was not significantly higher in urban areas than in rural areas. In addition, the prevalence of brucella infection among farmers was (65%), Veterinarian (52.9%), Veterinary Medical staff members (50%), Butchers (31%) and stockbreeders (30%). In addition, the overall positive brucella cases consist of (26.5%) farmers, (26.5%) butchers, Veterinarian (18.4%), Veterinary Medical staff members (16.3%) and stockbreeders (12.2%). The most prevalent clinical findings among the positive brucella cases was generalized weakness (38 subjects, 77.6%) followed by undulant fever (34 subjects, 69.4%) followed by profuse sweating (30 subjects, 61.2%) followed by joint pain, generalized pain and aches ,shivering ,loss of weight, testicular pain and finally loss of appetite was the last significant symptom (14 subjects, 28.6%). Twenty per cent of positive brucella cases had been absent from their work during the period of recurrent symptoms. Absence was a significantly reported phenomenon associated with brucella infection. From the previous results, it is concluded that brucellosis has high prevalence rate among high-risk occupational groups in Dakahliya Governorate, and the epidemiologic features of the disease have greatly changed so early detection and management of the disease as well as continuous monitoring for brucella among all occupational exposed personnel must be considered by local health authorities and veterinary health care organizations.