![]() | يوجد فقط 14 صفحة متاحة للعرض العام |
المستخلص , Angina pectoris is a frequent symptom in patients with hypertensive LVHdespite normal epicardial coronary arteries. One of the supposed mechanisms of occurrence of chest pain in those patients is the impairment of CFR. Coronary flow reserve is defined as the difference between maximal and baseline coronary flow. 40 hypertensive subjects were selected to enter our study and were subjected to the following: 1. History and clinical examination. 2. 12 lead ECG. 3. Transthoracic echo, ardiooraphy. 4. Coronary angiography. 5. Transoesophageal echocardiography. Subjects were divided into 3 groups: Group (A): Normal healthy control subjects. (10) Group (B): Hypertensive non-LVH. (13) Group (C): Hypertensive LVH. (17) We recorded peak diastolic velocity (PDV) and peak systolic velocity (PSV) on the bifurcation of main coronary artery during rest, after intravenous infusion dobutamine. We calculated CFR as the ratio of PDV and PSV after dobutamine. and PDV andPSV at resting baseline. We found that eFR was impaired in patients with hypertension either with or without LVB in comparison with the control group. Also the impairment ofCFR was more in LVH group than non LVII group. |