الفهرس 
Bacterial Skin InfectionOnly 14 pages are availabe for public view
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Abstract
Introduction: Erysipelas is a bacterial infection of the dermis and hypodermis with lymphatic involvement, caused mainly by group A-beta hemolytic streptococci. Aim of work: The aim of the present study is to describe the clinical forms and risk factors and to demonstrate the bacteriologic diagnosis of erysipelas patients Patients and methods: This study was conducted on 41 patients suffering from erysipelas. Their ages ranged from 21 to 85 years. Our results showed that the highest number of cases were females under 60 years. According to residence of studied patients, more patients were from rural areas, and erysipelas predominately involved in the leg. In our study, the disease recurred in 21 cases (51.2%), several factors have been suspected as local risk factors for recurrence of the disease including tinea pedis which was found in large number of cases followed by onychomycosis, lymphedema, trauma, and DVT. Results: Culture of samples from skin lesions demonstrated Beta hemolytic strept in only (29.3%) of patients. GAS were the major strept that cause erysipelas (67%), s. agalactiae(GBS) isolated in 16.5% and s. dysagalactiae (GCS)were isolated also in 16.5%. The results of serological testing indicated that most of patients (75.6%) showed negative ASO titre. Sensitivity testing indicated that ampicillin+sulbactam had the highest sensitivity (63.4%) followed by ofloxacin, then ciprofloxacin Hcl, cefoperazone, ceftazidime and sulphamethoxazol+trimethoprim, erythromycin and lastly ceftriaxone. Penicillins showed the lowest sensitivity (7.3%). Despite that the first line treatment was in all patients penicillin G, Penicillin had the highest resistance testing in our study. Conclusions: Erysipelas affects mainly females under 60 years. The usual site of infection is the leg. Culture of samples from skin lesions demonstrated GAS in only (29.3%) of patients. However,other organisms are isolated such as coagulase positive staph. Sensitivity testing indicated that ampicillin+sulbactam had the highest sensitivity. Treatment of erysipelas should be based on bacterial culture if possible to assure the best and rapid recovery.