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العنوان
Role of multislice CT in imaging of benign hepatic tumors /
المؤلف
Zaki, Mona Mahmoud Mohamed.
هيئة الاعداد
باحث / Mona Mahmoud Mohamed Zaki
مشرف / Salwa Mohamed Eteba
مشرف / Adel Galal El-Badrawy
مناقش / Awad Abd El-Aziz Bessar
الموضوع
Tumors-- Imaging.
تاريخ النشر
2009.
عدد الصفحات
160 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الأشعة والطب النووي والتصوير
تاريخ الإجازة
1/1/2009
مكان الإجازة
جامعة المنصورة - كلية الطب - Department of Radiodiagnosis
الفهرس
Only 14 pages are availabe for public view

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from 170

Abstract

Benign liver tumours are increasingly being diagnosed as a result of the widespread use of ultrasound, computed tomography and magnetic resonance in the evaluation of patients with non-specific abdominal symptoms.
These tumours are derived from the hepatocytes, bile duct epithelium, and endothelial cells. There are other cell systems in the liver, including connective tissue and muscle cells, macrophages,and neuroendocrine cells
Hepatic haemangioma is the commonest benign tumour of the liver, and has been reported in 0.4–20% of cases, Haemangiomas can occur in individuals of any age. Such tumours frequently occur in middle-aged women. Focal nodular hyperplasia (FNH) accounts for 8% of all primary tumours of the liver and is the second most common benign tumour of the liver after haemangioma. The incidence of hepatocellular adenoma has increased since 1960 and is estimated to be approximately 0.05–5 per million a year. Hepatic adenoma is extremely rare and is associated with the use of oral contraceptives, most frequently in women between 20 and 40 years of age.
The clinical manifestations of benign hepatic tumours vary; they may be asymptomatic or may present by acute abdominal pain. Asymptomatic cases are usually detected incidentally during routine physical examinations or imaging studies.
CT is now used as a basic approach to the whole body as radiography was in earlier years. Besides thoracic and vessel diagnostics, the assessment of the abdomen is the main role for CT . Although MRI has gained a increasing role in liver imaging, the availability and widespread distribution makes CT still the most commonly used method for upper abdomen diagnostics .
Imaging diagnostics of the liver are hampered by the fact that 20–50% of the population exhibit benign focal lesions, mostly cysts and hemangioma
The benefit of MDCT may be to better characterize smaller subcapsulary localized lesions where partial volume effects can be reduced due to higher spatial resolution. Higher spatial resolution may also be beneficial for small lesions, which often lack typical imaging features As with any other liver tumor mass, the capacity to produce high-quality non-axial reformations makes MDCT favorable for better imaging of the tumor site (e.g., pedunculated location) and its relationship to the surrounding tissue and organs .
Conclusion
Sixty-four-row MDCT, although developed primarily for cardiac imaging, has the potential to have a great impact on liver imaging as well Multiphasic and multiplanar capabilities, representing the added value of any MDCT scanner, starting with 4- slice, have been further improved: shortening of scanning time to a few seconds offers optimal separation of different vascular phases, thus improving lesion detection and characterization; z-axis resolution of 0.3–0.6 mm makes CT a true isotropic imaging modality, with the acquired volume perfectly suitable for multiplanar reconstructions and accurate organ and lesion volumetry; finally, the large volumetric coverage per rotation (40 mm) opens the era of functional imaging, represented by liver perfusion, with the exciting possibilities offered in terms of earlier diagnosis, lesion characterization and assessment of therapy response to be discovered in the next few years .