الفهرس 
Introduction
Obstructive Sleep Apnea SyndromeOnly 14 pages are availabe for public view
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Abstract
Introduction: Obstructive sleep apnea syndrome (OSAS) is a highly prevalent disorder with significant clinical consequences and major public health ramifications, we understand little about its pathogenesis. Upper airway imaging, however, has allowed us to begin to understand the biomechanical basis for obstructive sleep apnea syndrome and the mechanisms underlying the efficacy of various therapeutic intervention. Specification of the site of upper airway obstruction was found to be of value in planning the best line of management. Patients suffering from the disease mainly secondary to obstruction in the retroplatal area benefit from uvulopalatopharyngoplasty while those having obstruction in the retroglossal area benefit from maxilomandibular advancement. Aim of work: To study the anatomical risk factors of obstructive sleep apnea syndrome and its relation to the outcome of different treatment modalities. Patients and methods: The subjects in the present study were divided into two groups: the first group: forty seven patients were admitted to our department because of excessive day time sleepiness or snoring and the second group:ten subjects as a control group matched to patients with OSAS by age and sex. Control subjects were selected from workers of the hospital and relative of patients after verbal consent. Regarding subjects with obstructive sleep apnea there were 22 male (mean age, 37.95 years; range, 24-62 years) and 25 female (mean age, 47.6 years; range, 25-65 years). Results: Females with OSA were older than males (47.64 ± 9.58 years vs 37.95 ± 10.7 years) and are more obese (BMI= 32.16 ± 5.73 vs 37.25 ± 6.0 kg/m2, respectively, P = 0.005). There were no statistically significant differences between male and female according to AHI (56.35 ± 25.72 vs 40.4 ± 37.81, respectively, P = 0.115). The mean value of BMI and Neck circumference (NC) were higher with statistically significant difference in cases of OSAS compared to control healthy subjects (p=0.005 and <0.001) respectively. There was positive correlation between neck circumference and both soft palate area and MP-H distance. The mean values of soft palate (AP, width and area), Tongue area, Lateral pharyngeal wall thickness and Para pharyngeal pad of fat were higher in cases of OSAS compared to control cases with highly significant difference (p<0.001). Twenty five cases have obstruction at retroplatale and the remaining 22 have obstruction at combined retropalatal and retroglossal obstruction. Conclusions: Our results suggest that the upper airway in patients with OSAS is significantly smaller with respect to mean airway cross-sectional area compared with matched control subjects. The main site of obstruction in OSAS is retroplatal area but the retroglossal area may be the site of obstruction in some cases.