الفهرس 
I. IntroductionOnly 14 pages are availabe for public view
 |  | from | 164 |  |  |
| | | from | 164 | | |
Abstract
The present study was applied into experimental and clinical models.
The experimental one was
conducted on a number of 36 dogs in which an artificially induced abdominal wall defects (6 x10 cms),
including muscles and peritoneum were done. While the clinical model was conducted on a number of 33
animals of different species suffered from umbilical and abdominal hernias.
Bovine pericardium and tunica vaginalis were collected from the abattoir directly after slaughtering and
were preserved in glycerol 99.5 % at 4◦C until implantation.
Prosthetic herniorrhaphy was applied by using
Prolene mesh, glycerolized bovine pericardium and glycerolized tunica vaginalis for repairing the induced
abdominal wall defect and hernias in different animals by using two techniques for implantation including inlay
and underlay technique.
Gross examination which applied for two weeks postoperative and the dogs were euthanized at 60, 120,
180 days where postmortem and histological examination in addition to testing of the biomechanical properties
was applied.
The postmortem examination revealed that prolene mesh was encapsulated with dense fibrous
tissue with wrinkling of the mesh while bovine pericardium and tunica vaginalis were coated with connective
tissue layer and new peritoneum.
Higher grade of adhesion was recorded in animals implanted with prolene mesh than in animals
implanted with pericardium and tunica vaginalis.
Also this adhesion was higher in animals repaired by using
inlay technique without omentalization than in animals repaired by underlay technique with omentalization.
Histological examination revealed no changes of prolene mesh fibers that were surrounded by dense
fibrous tissue with presence of mild calcification at 6 months.
While biodegradation of pericardium and tunica.