الفهرس 
Aim of the workOnly 14 pages are availabe for public view
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Abstract
The present work was designed to evaluate how far the supplementary tablets ?Panox? in which the natural antioxidant vitamins (A,C and E) and trace elements (Zn and Se) are available within recommended levels could affect bone changes developed with aging. Male and female albino rats aged 3 month (mo) 8 mo old were used in this study as an explantation the present study suggested that the increased bone resorption coupled with the decreased bone formation being occurred secondary to the elevated PTH and the lowered calcitonin serum levels, could be ascribed to these age¬related bone changes. In contrast, it was evidenced that regular administration of panox (with mixture of antioxidant vitamins C, E & A and minerals Zn and Se) to the tested rats appeared to reduce the development of bone changes with aging, and this effect was more pronounced when panox was given at early age of 3 mo (with optimized bone mass) and continues to latter age of 20 mo, rather than when given at old age of 18 mo and continues to latter age of 20 mo. Conclusion : The present study suggest that the potential need to maintain adequate intake of natural antioxidant vitamins and minerals in the early age of life to reduce ?if not prevent? the onset of bone loss in the latter stages of life