الفهرس 
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Abstract
The present study was conducted at the Poultry Production Farm; Center of Agricultural Researches and Experiments; Faculty of Agriculture, Mansoura University, from November 2008 to January 2009. The objective of the present study was to evaluate the effect of a beta-adrenergic agonist drug salbutamol (hemisulfate salt;α-[(t-butylamino) methyl]4-hydroxy-m-xylene-α,α׳-diol) and folic acid (FA) or their combinations on growth performance, carcass characteristics, some blood parameters and histological structure of thigh muscle and liver in rabbits. The results obtained can be summarized as follows: 1. Growth performance and carcass traits of NZW rabbits: The weekly subcutaneous injection of S had no significant effect on final LBW of NZW rabbits at 14 weeks of age, but LBW of rabbits administered with 100 µg S/kg LBW was significantly heavier than of rabbits injected with 300 µg S/kg LBW. The concurrent weekly administration of S and FA significantly increased FI (from 6 to 14 weeks of age) and final LBW of rabbits administered with the intermediate and high doses of S plus FA (Groups 3 and 4) compared with their control group, but BWG and FC were not affected. 2. Blood parameters : Salbutamol injection in rabbits had a cholesterol lowering effect while levels of IGF-I and activities of CPK in plasma were increased and decreased, respectively, compared with the control group. Rabbits injected with the low and high doses of S ( Groups 2 and 4) exhibited higher activities of LDH and lower levels of creatinine in blood plasma with their control counterparts. Rabbits given the low dose of S (Group 2) recorded significantly higher concentration of plasma triiodothyronine (T3) compared with their control group. Plasma concentrations of T3 and IGF-I of rabbits given the intermediate dose of FA (Group3) were significantly higher than those of control rabbits, with no significant differences among other experimental groups. Rabbits administered with the low and intermediate doses of S plus FA ( Groups 2 and 3) exhibited significantly higher plasma concentrations of total protein and triiodothyronine (T3) and lower levels of creatinine compared with the control group. 3. Histological observation liver and of thigh muscle The high dose of salbutamol could produce a hypertrophy of muscle fibers with different degrees. The myofibrils became larger in diameter and appeared to be fused together. Sever disorganization of hepatic cells accompanied by more infiltrable fluids resulting in a squesed portal vein. Some necrotic and congested areas could also be seen.