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العنوان
Biomarkers of inflammatory bowel disease /
المؤلف
Kamal, Amany Abd El-Moteleb.
هيئة الاعداد
باحث / Amany Abd El-Moteleb Kamal
مشرف / Mohamed Ali Atwa
مشرف / Amany Ragab Youssef
مشرف / Nawal Abd El-Gelil Gharib
الموضوع
Crohn’s disease.
تاريخ النشر
2010.
عدد الصفحات
116 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الطب (متفرقات)
تاريخ الإجازة
1/1/2010
مكان الإجازة
جامعة المنصورة - كلية الطب - Department of Clinical Pathology
الفهرس
Only 14 pages are availabe for public view

from 126

from 126

Abstract

Inflammatory bowel disease is a generic term that refers to Crohn’s disease and chronic ulcerative colitis. Inflammatory bowel disease is precipitated by a complex interaction of environmental, genetic, and immunoregulatory factors. Biomarkers of IBD can be classified into serological, fecal and miscellaneous categories. Biomarkers of IBD can be used for IBD diagnosis, stratification, estimation of activity, prognosis, and prediction the response to therapy. Serological markers include, erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), antibodies directed against self-antigens and microbial antigens. Fecal biomarkers include the fecal excretion of leukocytes, leukocyte products, and serum proteins. Fecal markers have the advantage of having higher specificity for the diagnosis of IBD because their levels are not raised in extra-digestive processes.