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العنوان
Comparative pharmacological evaluation of the antiasthmatic effects of propolis, thymoquinone and curcumin /
المؤلف
El-Sayed, Noha Mohamed Shawky Ali.
هيئة الاعداد
باحث / نهى محمد شوقى السيد
مشرف / السيد محمد عمار
مشرف / ناريمان محمد جميل
مشرف / منار احمد نادر
الموضوع
Antiasthmatic.
تاريخ النشر
2011.
عدد الصفحات
144, 6 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الصيدلة ، علم السموم والصيدلانيات
تاريخ الإجازة
01/01/2011
مكان الإجازة
جامعة المنصورة - كلية الصيدلة - Department of Pharmacology
الفهرس
Only 14 pages are availabe for public view

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Abstract

DISSERTATION ABSTRACT (ONE PAGE A4) On comparing the antiasthmatic effects of propolis, thymoquinone and curcumin, it was found that thymoquinone may be the most potent mast cell stabilizer and the most potent inhibitor of iNOS mRNA expression in lungs of mice. It also exerted superior inhibitory effects on the aggregation of inflammatory cells in bronchoalveolar lavage fluid and in lung tissues. Propolis was found to exert the most potent bronchorelaxant effects and to show superior inhibitory effects on TGF-β1 mRNA expression. Curcumin showed the least inhibitory effects on all measured parameters except for the TNF-α mRNA expression levels in lungs of mice.