الفهرس 
Hematological malignancies
Cytogenetic characteristicsOnly 14 pages are availabe for public view
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Abstract
The bicuspid aortic valve (BAV) is one of the most common congenital heart valve disorders, affecting 1 to 2% of the population. The BAV may be sporadic or familial. The BAV may be associated with significant valvular dysfunction and lead to aortic stenosis (AS) or aortic regurgitation (AR) and is at risk for infective endocarditis (IE). Additionally, the BAV is associated with aortic wall abnormalities, including coarctation of the aorta (COA), aortic dissection, and ascending aortic dilation and aneurysm formation. Most patients with a BAV will develop some complication during life and thus require continued surveillance and appropriate surgical therapy. This review will encompass the anatomy, pathology, genetics, clinical features, imaging, valvular, and extravalvular complications, as well as the underlying pathophysiology of the aortic wall complications of the BAV. Recommendations for medical and surgical management of the BAV and associated aortic disease will be reviewed in this article.