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العنوان
Nasopharyngeal carcinoma /
المؤلف
Markus, Nagah Ragab.
هيئة الاعداد
باحث / نجاح رجب مركوس
مشرف / ناديه إبراهيم عطوان
مشرف / فيروز الترجمان
مشرف / مي علي علي
مناقش / توكل جميل السيد علي
مناقش / ساميه يوسف حجاج
الموضوع
Nasopharyngeal Neoplasms-- diagnosis. Nasopharyngeal Neoplasms-- pathology.
تاريخ النشر
2010.
عدد الصفحات
92 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
أمراض الدم
تاريخ الإجازة
1/1/2010
مكان الإجازة
جامعة المنصورة - كلية الطب - قسم الباثولوجى
الفهرس
Only 14 pages are availabe for public view

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from 96

Abstract

Nasopharyngeal Carcinoma is a rare neoplasm in most countries of the world occurs with exceptionally high frequency among Chinese. It is well established that (NPC) is a malignant epithelial tumor derived from nasopharyngeal surface epithelium. Mostly NPC diagnosed in people from age 30 to 60 years age. Male are more likely to develop (NPC) than female. NPC is classified according to (WHO) into three main groups: - Sq. cell Carcinoma (Keratinized Squamous Cell Carcinoma). - Non – Keratinized Carcinoma showing evidence of differentiation with a maturation sequence that result in cells in which squamous differentiation is not evident on light microscopy. - Undifferentiated Carcinoma (undifferentiated Carcinoma of Nasopharyngeal type. The presenting signs and symptoms are often subtle requiring a high index of suspicion for early diagnosis. Different studies have been done to study the relation between ( NPC ) and EBV, most of them confirm that there is a regular association between EBV-DNA and undifferentiated NPC as most of the patients have high levels of anti bodies to EBV antigens, EBV genome is present in NPC Cells and virus can be recovered from cultured NPC Cells. Nasopharyngeal Carcinoma is particularly sensitive to radiation therapy making it the first line of treatment – surgery and chemotherapy are used in certain cases.