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العنوان
Microdetermination of some pharmaceutical ome compounds in their pure and trade forms using various analytical techniques /
المؤلف
Ali, Wael Mohammad Ibrahem.
هيئة الاعداد
باحث / Wael Mohammad Ibrahem Ali
مشرف / Magda A. A. Akl
مناقش / Ragaa El-Sheikh Shoheib
مناقش / Mona Abdel Aziz Ahmed
الموضوع
pharmaceutical compounds. Microchemistry.
تاريخ النشر
2011
عدد الصفحات
130 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
Analytical Chemistry
تاريخ الإجازة
1/1/2011
مكان الإجازة
جامعة المنصورة - كلية العلوم - Department Of Chemistry
الفهرس
Only 14 pages are availabe for public view

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Abstract

In the present study, different analytical techniques (viz.: solvent extraction, precipitation and flotation) were used for the determination of micro-amounts of some selected drugs; the antitussive drug: Dextromethorphane (DEX), the antispasmodic drug: Hyoscine n-butylbromide (HBB), the antihypertensive drug: Losartan potassium (LSR) and the anti depressant drug: Sertraline hydrochloride (SER). These drugs, besides their medical importance, possess nitrogen atoms that give them great ability to form stable ion pairs with cobalt (II) and/ or molybdenum (V) thiocyanate and bismuth (III) tetraiodide complexes which are widely used in pharmaceutical analysis. The formed ion pairs are separated by the proposed separation techniques(precipitation, solvent extraction and flotation) followed by spectrophotometric determination of the investigated drugs in pure forms and in pharmaceutical preparations.