الفهرس 
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Abstract
component therapy has replaced whole-blood transfusion in most countries with advanced medical care, mainly for three reasons: (1) better maintenance of quality, (2) more effective use of the blood and (3) more efficient and appropriate dosage to the patients. Blood components can be prepared either by separation of whole blood or by apheresis. So far the basic supply of the normal blood components stems from the collection of whole blood. By relatively simple procedures herniation a red cell concentrate, a platelet concentrate (PC) and a plasma unit can be obtained from one normal blood collection. The blood is frequently collected at mobile sites, at some distance from the blood-processing laboratory, which increases comfort for the donors. The procedure itself only takes about 15 minutes. Blood-derived biomaterials include fibrin glue ”also called fibrin sealant (FS)”, platelet gel (PG), and platelet fibrin glue. They are used in many surgical fields because of their functional properties and unique physical advantages compared to synthetic products. Fibrin glue ,also called fibrin sealant (FS), is obtained by mixing a fibrinogen-rich fraction with a concentrate of thrombin . The mixing of these two components leads, within a few seconds, to the formation of a semi-rigid to elastic clot, mimicking the last step of blood coagulation to achieve haemostasis. The clot consolidates and adheres to the surgical application site.