الفهرس 
Embryological ConsiderationsOnly 14 pages are availabe for public view
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Abstract
Hirschsprung ’s disease is a frequent cause of intestinal obstruction in the newborn and I or constipation in infants and children. The surgical treatment of Hirschsprung ’s disease has traditionally been staged, with an initial defunctioning colostomy at the time of diagnosis followed some months later by the definitive surgical procedure, and in many cases by a third procedure to close the colostomy.This study was undertaken to explore the feasibility of performing the definitive treatment of Hirschsprung’s disease as one-stage approach. This was accomplished by the analysis of the results of one-stage ERPT in children with the standard or long-segment Hirschsprung’s disease. In the few patients with ultra-short aganglionosis, the results of anorectal myectomy were investigated as well. Children, who underwent multi-stage ERPT or other multi-stage procedures served as a control groups.The material of the current study composed of 172 patients with proven tissue diagnosis of Hirschsprung’s disease. Of these 172 patients, 9 had been treated at Tanta University Hospital. The rest of patients (163) had been treated at CS Mott Children’s Hospital in the University of Michigan Medical Center. The charts of those patients had been reviewed. Personal interview with the patients and I or their relatives was carried out during their hospitalization and I or during their out-patient follow up visits. These 172 patients represent all children with Hirschsprung’s disease who had a fairly complete medical records and regular follow up during one year study period at Tanta University and from July 1974 through August 1993 at the University of Michigan Medical Center.