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Abstract At present, coronary stent are mainly used for two purposes; as a bail-out therpy for theatened or abrupt vessel closure complicating PTCA; and as an elective techninque for improving suboptimal angioplasty result, treatment of restenotic lesions in the native coronary arteries, and stenosis or restenosis of the venous bypass grafts. Previous studies revealed that stent placement is highly effective in treating threatened or abrupt vessel closure due to PTCA induced dissection and can reduce mortality, emergency CABG, and myocardial infarction comparable to that after uncomplicated PTCA. More recently, the BENESTENT I and STRESS randomized trials compared elective stenting and angioplasty in treating de novo native coronary artery lesions. Both studies demonstrated significant reduction in the restenosis rate in the group treated with stents. In addition, in the BENESTENT I trial, the reduction in the restenosis rate was associated with a significant reduction in the major clinical events in the group randomized to stents. There is still concern, however, in the clinical use of stents about three potential complications: the risk of stent thrombosis, the occurrence of stent restecosis, acd vascular complictions. |