![]() | Only 14 pages are availabe for public view |
Abstract Cortisol drops gain enterance to the ocular tissues and fluids either via the direct routes ( Trans-conjunctiva and sclera or trans-corneal) and to a lesser extent via the systemic circulation and cortisol is released either through the aqueous outflow or trans-scleral through the lymphatic drainage. Central cornea shows the highest concentration of cortisol, following it are the peripheral cornea, sclera, iris, optic nerve, aqueous, lens and vitreous respectively. The concentration of cortisol is therapeutic in all ocular tissues for 24 hours, except in lens snd vitreous in which the concentration is not therapeutic. The concentration in aqueous is therapeutic only for 15 minutes. |