الفهرس 
Biological activity of nucleosidesOnly 14 pages are availabe for public view
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Abstract
The present work is a part of program deals the design and synthesis of some new 4(3H)-quinazolinone derivatives and their reactivity towards different monohalosugars. The study of different selected substitution in correlation with their spectra1 and biological activity was also , of special considered I, 6,8-Disubstituted 2-mercapto-3 aryl-4 quinazolinone To fulfill this purpose,the target compounds (CVIIrj and CVIII) were prepared by different methods Reaction of 3,5-disubstituted anthranilic acid with aryl isothiocyanate in absolute ethanol gave, 6,8-disubstituted 3-aryl-4(3H)-quinazolinone (CVII a,b,e,g,h,i 1 3,5-Disubstituted anthranilic acid with primary arylamines carbon disulphide in the presence of potassium hydroxide in absolute ethanol, gave 6-substituted 2-
mercapto-3-aryl-4(3H)-quinazolinone (CVII c,d,f) The fusion of 3,5-disubstituted anthrani lic acid with Nphenylthiourea in an oil bath gave the corresponding quinazolinone e.g. (CVIIa). The treat.ment of 6,8-disubstituted-2-mercapto-3-ary1- 4(3H)-quinazolinone with Lawson reagent or phosphours pentasulphide in absolute toluene as a solvent, 6,8-disubstituted 2-mercapto-3-aryl-4(3H)-quinazolinethione was obtained.