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Abstract Neonatal sepsis is one of the major problems that meet the pediatrician. Saving life in these critically patients is of practical importance, we cannot put the expenses of the treatment in the face of saving their life. In our piecework we have thrown the light on the different lines used in management, proper antibiotics, G-CSF, G-CSF plus IVIG. We tried in 60 septic neonates with late onset neonatal sepsis irrespective to their neutrophilic count, one third were given the standard antibiotic therapy, other one third were given G-CSF in addition to the standard antibiotic therapy, and the third were given G-CSFan(fVftiprti crr s’crruthr’ therapy. Once diagnosis of sepsis is suspected by a thorough history dng, clinically by having a clinical scoring system of 3 or more, 1 hematological score 3 or more, sepsis work up is done (blood ire, CSF culture, etc) and each neonate was randomly fallen a specific group and started antibiotic therapy. In addition, Jier G-CSF in a dose of 10 meg/kg/kg subcutaneously for 3 ‘ccessive days. Or G-CSF plus IVIG in a dose of 500 mg 1once intravenously was given, and cases with negative blood - e were excluded. ..ood culture was positive in 100% of cases of suspected sepsis, rid the most common causative organism was klebsiella (43%), Lowed by Staph. aureus (23.3%), then E.Coli (16.7%). |