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Abstract This study was conducted to identify possible neurobehavioral effects among workers occupationally exposed to pesticides. The results indicated that long-term and clinically non-toxic exposure to OP pesticides have definite and quantifiable effects upon apparently asymptomatic human beings as reflected by worse performance on 7 of 13 neurobehavioral tests. Performance on a number of neurobehavioral tests was significantly worse for those with lesser years of education and those with more years of exposure, the results supporting the suggestion that the OP exposure is the causative agent. Numbness and dizziness were the only different symptoms and signs reported as significantly higher in the exposed than the control participants. However, all symptoms and signs assessed were significantly increased with increasing years of exposure to pesticides. Serum acetyl cholinesterase as an indicator of exposure, was significantly higher in the exposed than control participants but was not correlated with either poor performance r abnormal neurological symptoms and signs. However, a trend towards lower AChE as associated with abnormal neurobehavioral performance and abnormal |