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Abstract Testosterone is important in maintaining of seminiferous epithelium. This action of testosterone is mediated through androgen receptors found within the Sertoli cell and on peritubular and Leydig cells (Butler et al, 1992). Testosterone converted into dihydrotesto sterone by 5 a. reductase enzyme. The two androgen bind to the same androgen receptor complexes, found within the Sertoli cell and Leydig cells. Testosterone receptor complex regulates gonadotropin secretion, and is responsible for muscle development, dihydrotestosterone receptor complex control male secondary sexual characters during puberty (Bremner et al, 1994). Serum testosterone is responsible for changes in Tanner genital and pubic hair stages. Enlarged testicular size, pubic and axillary hair development are attributed to serum testosterone (Jave-Saurez, 2004). Androgen action includes regulation of gonadotropin secretion by hypothalamic-pituitary system, initiation and maintenance of spermatogenesis, formation of male phenotype |