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Abstract ucose-6-phosphate dehydrogenase deficiency is the common enzyme deficiency producing disease in (Beutler, 1978). the present study 28 patients with acutetic anemia due to GSPD deficiency, their ages between 7 months and 9 years, 27 of them were and one was female, all were subjected to the ving — horough history taking with special emphasis on ily history of similar conditions. onsanguinity. ge of the first attack of hemolysis. of the offending agent. nical examination Dratory investigations in the form of Pull blood picture, hematocrit , reticulocytic index and serum bilirubin (total , direct and irect). r100d glucose and serum insulin. hse laboratory investigations are again done in uiescent stage in addition to qualitative tion of G6PD enzyme by colorimetric technique. results was that during acute hemolysis, there |