الفهرس 
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Abstract
Aim of the study The aim of the study is to fined relationship between liver cirrhosis and osteoporosis and the role of Parathormone, and vitamin D in development of osteoporosis in male patients with liver cirrhosis.
Patients and methods Thirty male patients, in addition to ten healthy controls were included m this study. They were classified into 3 groups according to Child - Pugh classification .Group 1(10 patients with Child A class)Group 11(10 patients with Child B class). Group 111(10 patients with Child C class) and Group VI ( 10 healthy male controls).
All patients and control groups were subjected to full history taking, clinical examination, laboratory investigations including urine and stool analysis ^complete blood picture , liver function tests as serum bilirubin,, Albumin, Prothrombin time ,serological markers for hepatitis(HbsAg, HCV antibodies) ,estimation of serum Calcium: (Total and ionized) and estimation of Parathormone and 25 (OH) vitamin D3 level in blood and radiological investigations including abdominal ultrasonography confirms diagnosis of liver cirrhosis and estimation of bone mineral density (BMD) by Dual Energy X ray Absorptiometry(DEXA) technique of the lumber spine .
Results The primary finding of this study was that BMD is significantly lower in cirrhotic patients than controls and this reduction in BMD was statistically significant. We found that there was reduction in BMD of cirrhotic patients with deterioration of liver functions from Child pugh A to C groups. Osteopenia was demonstrated in 3 patients (30%) in group I 10 patients (100%) in group II and only in 1 patient (10%) in group III but osteoporosis was demonstrated in 9 patients (90%) in patients patients in group III.
We found that BMD decreased with higher level of serum bilirubin. This result was highly statistically significant (P=0.003).
We found that BMD decrease with low levels of serum albumin and this result was highly statistically significant (P=0.000).