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Abstract Both endogenous and exogenous factors are involved in the regulation of endocrine secretions. Among the exogenous ones, light plays an important role in animals and humans. Melatonin is synthesized by the pineal gland mainly during the biological night and exerts its effectgs on the reproductive system through specific high affinity receptors in the hypophyseal pars tuberalis and hypothalamic suprachiasmatic nucleus. This study is aimed to evaluate the changes in melatonin secretion in blind males, in a trial to determine whether blind’s secretion. We aimed also to study the sexual and reproductive functions of such males. To approach our goal 22 totally blind adult healthy males were selected and 26 age matched sighted healthy adult males served as control. Both groups were married for at least 2 years. All studied subjects were submitted to general and local examination & full history taking, stressing upon age of puberty, number of children and sexual function including : frequency of intercourse, degree of erection, libido and state of ejaculation. |