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Abstract Community acquired pneumonia remains a leading cause of morbidity and mortality worldwide and has significant financial implications for health-care system, pneumonia remains a major reason for admission to hospital and a common cause of death. Acute exacerbation of chronic bronchitis (AECB), a COPD condition, also represents a significant and increasing community-acquired respiratory tract infection. Moreover, it was found that in COPD patients, bacterial infections are judged to cause at least half of exacerbations, and it is advised that the choice of antibiotic is important because the rise in bacterial resistance has made older agents less effective. Increases in the number of newly identified or previously unrecognized pathogens, the availability of new antimicrobial agents, and the evolution of bacterial resistance mechanisms make the appropriate microbiological investigation of the patients admitted with lower respiratory tract infection an important issue. Several factors favor microbiological investigation. First, the pathogen identified may be resistant to the chosen empiric antibiotic therapy. Second, identification of the pathogen may allow streamlining of antibiotic therapy, thereby reducing cost and possibly reducing the development of antibiotic resistance. Third, accurate epidemiologic data are required in order to design appropriate empiric therapy. There for, the aim of this work was to study the common pathogens (microorganisms) that appear in sputum culture among patients in chest department, Menoufiya University |