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Abstract
Background: Both thallium-201 single photon emission computed tomography (SPECT) and dobutamine stress echocardiography (DSE) have been used to identify viable myocardium, although DSE has been demonstrated to be the less sensitive of the two. But evaluation by DSE, in which conventional assessment of wall motion based on visual interpretation of endocardial excursion and myocardial thickening, suffers from the limitations of qualitative method and is subjective and experience dependent. The recently developed pulsed-wave Doppler tissue imaging (DTI) may permit objective and quantitative assessment of viable myocardium.
Objective: To determine the value of new technique pulsed-wave DTI in assessing myocardial viability in patients with acute myocardial infarction (AMI) by studying the concordance between dobutamine stress DTI and thallium 201 SPECT.
Methods: Myocardial contraction and perfusion were assessed in 30 patients with AMI using low dose and high dose dobutamine DTI and thalliumr201 SPECT to predict segments with reversible dysfunction. The DTI data were compared with thallium-201 SPECT on the basis of a 16 segment ventricular model.