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Abstract
The cardiovascular and respiratory system cannot be thought of independently and should be considered to function as a single unit, the cardiorespiratory system. The mitral valve is the closest to the lungs, therefore, any pathological lesion involving it, will result in increase in left atrial pressure, increase in the pulmonary venous pressure and reflex increase in pulmonary arteriolar resistance leading consequently to pathological pulmonary vascular changes.
Pulmonary function tests measure the ability of respiratory system to accomplish its main task, which is gas exchange by assessing ventilation, diffusion, gas exchange, static and dynamic mechanical properties of the respiratory system.
The aim of this study is to clarify the possible pulmonary functional derangement in a group of children with isolated mitral valve diseases at different stages using spirometry.
The study was carried out on 50 patients. 30 patients with isolated mitral valve disease, 22 patients with MR (groupI) and 8 patients with DM (group II). 20 apparantly healthy children were taken as control (group III).
All the groups were subjected to the following:
- Complete clinical evaluations (history and physical examination).
- Laboratory investigations as CBC , CRP , ESR and ASOT.
- Plain X-ray chest and heart.