الفهرس 
Diabetes mellitus
Subjects and methodsOnly 14 pages are availabe for public view
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Abstract
A large number of changes, distant from the site or sites of inflammation and involving many organ systems, may accompany inflammation. These systemic changes have since been referred to as the acute-phase response, even though they accompany both acute and chronic inflammatory disorders
Acute phase reactants such as C-reactive protein and sialic acid may predict risk of developing Type 2 diabetes mellitus, as well as being markers of diabetes microvascular and macrovascular complications
C-reactive protein was initially described as an acute-phase reactant that binds pneumococcal capsular polysaccharide. CRP is highly sensitive marker of inflammation and tissue damage, and levels can rise to more than 500 mg per liter in a variety of acute or chronic inflammatory conditions. Base-line CRP levels are roughly divided into population thirds of less than 1 mg per liter, 1 to 3 mg per liter; and more than 3 mg per liter. The introduction of high-sensitivity assays for CRP has permitted the routine measurement of base-line CRP, an option that was formerly available only research laboratories