الفهرس | Only 14 pages are availabe for public view |
Abstract ,SUMMARY. I AND CONCLUSIONS II,’”, >;,>:,”<’ fi , • . ,.’ ”,’ ”, , lJ..! SUMMARY AND CONCillSION Blood is a biological fluid. consisting of formed elements. the red blood cells. the white blood cells and • the platelets. all suspended in a fluid media. the plasma. These formed elements require a source of energy in order to maintain its function and to survive in the blood for its normal life span. The main source of energy is glucose. Preserved blood is expected to vary considerably from that circulating inside the vessels. The aim of the present work is to determine the possible effects of blood storage in CPDA-l on the plasma proteins ( total and differential ) and on some immunoglobulins. During donation of blood for storage. certain precautions are taken to avoid harmful effects for the blood donated. Blood was received in plastic bags containing CPDA-l anticoagulant. It was then thoroughly mixed and divided into 4 aliquots through the connecting tube and kept Ln the blood bank refrigerator at 4°C. These bags were examined in the first day of storage, after one week. three weeks and five weeks of storage. They were examined for I _ Plasma proteins ( total and differential ). IgG, IgM. and 19A. In our work, we found no significant difference in the 64 plasma proteins (total and differential ) between the levels of the first day and the levels after five weeks of storage. Also there was no significant change in the concent- .rations of IgG, IgM and 19A after five weeks of storage. from this, we conclude that many useful fractions can be ..obtained from the plasma of the stored CPDA-l blood. One of these fractions is the albumin which is the major budgetary item for many hospital blood banks. It is used mainly for hypovolemia in surgery or trauma and for chronic hypoalbuminemia in nephrosis, cirrhosis and the malabsorption syndrome and may be used to maintain the obligatory extracellular space, as in severe burns. Immunoglobulins are also useful preparations and can be used effectivly in the treatment of hypogammaglobulinemia. |