الفهرس 
Immunosuppression
MalignancyOnly 14 pages are availabe for public view
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Abstract
The aim of the present work was to study the incidence, management
and outcome of post-transplant complications secondary to immunosuppressive drugs and comparing it with that cited in literatures and
its impact on patients and graft survival. The material of this work comprised 150 patients who received
living related donor kidney transplantation. Those patients were subjected to thorough clinical, laboratory and radiologic evaluation.
They were given immunosuppressive drugs in different protocols. Minimum clinical follow up after transplantation was one year.
Early post-operative complications included: Hypertension (34%),
Diabetes (4%) which were easily controlled, acute ciclosporin nephrotoxicity (33.3%) and urinary tract infection (48%). Late complications comprised many items, of which hepatic dysfunction (3.3%), aseptic bone necrosis (3.3%),malignancy and chronic ciclosporin nephrotoxicity were the most important. We have concluded that immunosuooressive drugs are not without risk, however, they are mandatory to prevent graft rejection. Yet, there is no ideal immunosuppressive drug. We hope that in the near future new immunosuooressive drugs may be discovered with minimal
complications to decrease the morbidity and mortality of these drugs in kidney transplant recipients and give hope to patients and doctors for a better future.